The accumulation of MRP14⁺ and MRP8⁺ cells promoted by rMRP14 in the liver during rodent malaria.

<p>(a) The accumulation of MRP14⁺ cells in the liver of mice injected with rMRP14 or PBS after Pb-infection. Bars; 50 µm. (b)The accumulation of MRP14⁺ cells in the liver of rMRP14-injected naïve mice and PBS-injected controls. Bars; 50 µm. (c) The number of accumulated MRP8⁺ and MRP14⁺ cells in the liver of mice injected with rMRP14 or PBS after Pb-infection (n = 5). (d) The number of accumulated MRP8⁺ and MRP14⁺ cells in the liver of naïve mice injected with rMRP14 or PBS (n = 5). (e) The number of peripheral blood leukocytes of mice injected with rMRP14 or PBS after Pb-infection (n = 5). (f) The accumulation of MRP14⁺ cells in focal necrosis area of the liver in mice injected with rMRP14 or PBS after Pb-infection. Bars; 50 µm. Graphs show mean and SD of each group. Data are representative of two independent experiments. ^*<i>P</i> < 0.05; n.s., not significant.