Modeling the functions of condensin in chromosome shaping and segregation - Fig 2

<p>(<i>A</i>) Asphericity as a function of the strength <i>F</i>_cond and the threshold distance Δ of inter-condensin attractions, with . (<i>B</i>) Asphericity as a function of the loop-holding force <i>F</i>_loop under three pairs of different parameters of the attractions. (<i>C</i>) Chromosome monomer density as a function of the distance from condensin at the points <i>D</i> and <i>E</i> shown in panel <i>A</i>. (<i>D–G</i>) Example of the configurations observed at the end of the simulations at each point of <i>D–G</i> shown in panel <i>A</i>. The blue line is the chromosome and the red points are condensins. All simulations are performed employing a single chromosome condition with the number of monomers <i>N</i> = 5000 and the number of loops <i>M</i> = 100.