<p>After direct LDIR for 24 hours or in the bystander condition, the cells were subjected to lysis and immunoblot analyses. The results are representative of three independent experiments, and the intensity of each immunoblot signal compared with that of α-tubulin was quantified using ImageJ software; the quantity is shown directly under each blot.</p
<p>Cells were transfected with the corresponding plasmids carrying the mutations of interest, LDLR w...
<p>(A and B) PCSK9-488 internalization in the presence of J16 (top row), LDL and J16 (middle row), o...
<p>(A) Uptake of <sup>125</sup>I-LDL, (B) degradation of <sup>125</sup>I-LDL and, (C) uptake of FITC...
<p>(A) Panels show lactate dehydrogenase (LDH) release in LLC-PK<sub>1</sub> (left), MDCK (middle), ...
<p>The transfected cells were incubated in serum-free media containing 20 μg/ml Dil-LDL at 37°C for ...
<p>BV173 and K562 cells were treated with 10 mM HP-β-CyD for the indicated times, after which STAT5,...
<p>For confocal analysis of LDLR at cellular membrane and LDL uptake, CHO-<i>ldlA7</i> transfected c...
<p>(<b>A</b>) – Western blots for phospho-IκBα and p44/42 MAPK with corresponding graphs depicting r...
(A) Immunoblot validation of LC-MS/MS data showing phosphorylation of Rb residues S249, S612, S807, ...
<p>Panel <b>A</b> shows inhibition of light chain (LC)-stimulated phosphorylation of ERK ½, and pane...
<p>ScN2a-3-22L cells were incubated with Alexa Fluor 488-conjugated LDL (4 µg/ml) for 6 h. After the...
<p>Normal rat kidney (NRK) cells stably expressing GFP-LC3 were left untreated (A) or treated with 2...
<p>A) RT-PCR analysis of LRP5 and LRP6 levels in HeLa cells transfected either with cognate pools of...
<p><i>A.</i> hTTLL12 (hTTLL12_A-E) or Control (Control_A, _B, _D, _E) clones were harvested in Laemm...
<p>(A and B) Western blot showing APLP2, PCSK9, or Transferrin receptor (TFNR) levels in input fract...
<p>Cells were transfected with the corresponding plasmids carrying the mutations of interest, LDLR w...
<p>(A and B) PCSK9-488 internalization in the presence of J16 (top row), LDL and J16 (middle row), o...
<p>(A) Uptake of <sup>125</sup>I-LDL, (B) degradation of <sup>125</sup>I-LDL and, (C) uptake of FITC...
<p>(A) Panels show lactate dehydrogenase (LDH) release in LLC-PK<sub>1</sub> (left), MDCK (middle), ...
<p>The transfected cells were incubated in serum-free media containing 20 μg/ml Dil-LDL at 37°C for ...
<p>BV173 and K562 cells were treated with 10 mM HP-β-CyD for the indicated times, after which STAT5,...
<p>For confocal analysis of LDLR at cellular membrane and LDL uptake, CHO-<i>ldlA7</i> transfected c...
<p>(<b>A</b>) – Western blots for phospho-IκBα and p44/42 MAPK with corresponding graphs depicting r...
(A) Immunoblot validation of LC-MS/MS data showing phosphorylation of Rb residues S249, S612, S807, ...
<p>Panel <b>A</b> shows inhibition of light chain (LC)-stimulated phosphorylation of ERK ½, and pane...
<p>ScN2a-3-22L cells were incubated with Alexa Fluor 488-conjugated LDL (4 µg/ml) for 6 h. After the...
<p>Normal rat kidney (NRK) cells stably expressing GFP-LC3 were left untreated (A) or treated with 2...
<p>A) RT-PCR analysis of LRP5 and LRP6 levels in HeLa cells transfected either with cognate pools of...
<p><i>A.</i> hTTLL12 (hTTLL12_A-E) or Control (Control_A, _B, _D, _E) clones were harvested in Laemm...
<p>(A and B) Western blot showing APLP2, PCSK9, or Transferrin receptor (TFNR) levels in input fract...
<p>Cells were transfected with the corresponding plasmids carrying the mutations of interest, LDLR w...
<p>(A and B) PCSK9-488 internalization in the presence of J16 (top row), LDL and J16 (middle row), o...
<p>(A) Uptake of <sup>125</sup>I-LDL, (B) degradation of <sup>125</sup>I-LDL and, (C) uptake of FITC...