Additional file 1: of Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer

Figure S1. ES2 and OVCAR3 cells resistance to hypoxia mimicked with CoCl2. Comparison of ES2 and OVCAR3 cells resistance to hypoxia mimicked with CoCl2 for 48 h of assay for A. ES2 and OVCAR3 cells in which values were normalized to the respective control, and B. ES2 and OVCAR3 cells with non-normalized to control values. N selected – cells selected under normoxia; H selected – cells selected under hypoxia mimicked with CoCl2. Results are shown as mean ± SD. Asterisks represent statistical significance between ES2 and OVCAR3 cells. *p < 0.05, **p < 0.01, ***p < 0.001 (Independent samples T tests). (TIFF 127 kb