Additional file 1: of Single-strand DNA processing: phylogenomics and sequence diversity of a superfamily of potential prokaryotic HuH endonucleases

Figure S1. Distribution of protein length in each subclass; Figure S2. Coverage of HMM profiles and proteins for each subclass; Figure S3. ab initio search for conserved motifs with MEME in proteins of each subclass; Figure S4. Distribution of the distances (AA) between the HuH and Y motifs in proteins of each subclass; Figure S5. Genome size and the occurrence of TnpAY1; Figure S6. Short repeated sequences in subclass 2.4 TnpAREP; Figure S7. Homology modelling of proteins with extra domains in the conserved core domain; Figure S8. C-terminal subclass specific domains; Figure S9. Additional subclass specific domains; Figure S10. Subclass 2.4, REP insertions in coding sequences; Figure S11. Analysis of conservation in subclasses of the key residues involved in 5′ GTAG guide sequence binding; Figure S12. Number of intra genomic copies of each subclass; Figure S13. Percentage of sequence alignment identities between pairs of TnpAY1 sequences. (DOCX 2899 kb