Figure S5. qPCR validation of the microarray data in gain and loss-of-function experiments. a, a’ qPCR validation of selected genes from the microarray in a gain-of-function approach. (a) Region 1 and (a’) Region 2. b, b’ qPCR validation of selected genes from the microarray in a loss-of-function approach using dmrt2a-MO. (b) Region 1 and (b’) Region 2. *P < 0.05, **P < 0.01, ***P < 0.001, ns: not significant. P-values were generated using a two-tailed t-test. (TIF 1349 kb
Characterization of early neural development and larval behavioral tests in WT and dyrk1aa KO fish. ...
Table S1. Identification of additional r4, r5 and r6 genes. This file represents the data downloaded...
Figure S1. Comparison of R2 element insertion site. Figure S2. Nine clones of R2Ol obtained from med...
Figure S3. Microarray data. a, b List of all the genes obtained in the microarray with FC > 2 or FC ...
Figure S7. dmrt2a expression pattern using in situ hybridisation after gain and loss-of-function exp...
Figure S1. TALEN pairs. a Alignment between TALEN P1 and dmrt2a sequence. b Alignment between TALEN ...
Figure S6. No misexpression was found in the validated genes after dmrt2a gain and loss-of-function ...
Figure S4. Gene Ontology (GO) analysis of the microarray data. a, b Most significant GO terms associ...
Figure S2. HA-Dmrt2a dynamics after heat-shock. Immunostaining showing the expression of the HA-Dmrt...
Figure S2. RT-qPCR confirms tissue specific gene expression in tissue specific sorted cells. (A) Fro...
Nucleotide and predicted amino acid sequence of mutant alleles. A, B. Nucleotide and predicted amino...
Figure S1. Data quality assessments. a Pearson correlation of genome wide coverage between replicate...
Is a plot showing the sensitivity of MiRDeep2 for identification of known miRNAs from zebrafish. The...
Figure S7. Scheme for generating gbx1 mutant line. (A) Schematic showing the 20 nucleotide (orange t...
Differentially expressed genes in BBS model. All genes exhibiting significant changes in bbs1-deplet...
Characterization of early neural development and larval behavioral tests in WT and dyrk1aa KO fish. ...
Table S1. Identification of additional r4, r5 and r6 genes. This file represents the data downloaded...
Figure S1. Comparison of R2 element insertion site. Figure S2. Nine clones of R2Ol obtained from med...
Figure S3. Microarray data. a, b List of all the genes obtained in the microarray with FC > 2 or FC ...
Figure S7. dmrt2a expression pattern using in situ hybridisation after gain and loss-of-function exp...
Figure S1. TALEN pairs. a Alignment between TALEN P1 and dmrt2a sequence. b Alignment between TALEN ...
Figure S6. No misexpression was found in the validated genes after dmrt2a gain and loss-of-function ...
Figure S4. Gene Ontology (GO) analysis of the microarray data. a, b Most significant GO terms associ...
Figure S2. HA-Dmrt2a dynamics after heat-shock. Immunostaining showing the expression of the HA-Dmrt...
Figure S2. RT-qPCR confirms tissue specific gene expression in tissue specific sorted cells. (A) Fro...
Nucleotide and predicted amino acid sequence of mutant alleles. A, B. Nucleotide and predicted amino...
Figure S1. Data quality assessments. a Pearson correlation of genome wide coverage between replicate...
Is a plot showing the sensitivity of MiRDeep2 for identification of known miRNAs from zebrafish. The...
Figure S7. Scheme for generating gbx1 mutant line. (A) Schematic showing the 20 nucleotide (orange t...
Differentially expressed genes in BBS model. All genes exhibiting significant changes in bbs1-deplet...
Characterization of early neural development and larval behavioral tests in WT and dyrk1aa KO fish. ...
Table S1. Identification of additional r4, r5 and r6 genes. This file represents the data downloaded...
Figure S1. Comparison of R2 element insertion site. Figure S2. Nine clones of R2Ol obtained from med...