<i>TNF-α</i> polymorphisms and TNF-α expression among severe fever with thrombocytopenia syndrome patients with different outcomes.

<p>(A) Serum TNF-α levels between acute phase and convalescent phase of hospitalize SFTS patients. (B) Serum TNF-α levels between SFTS patients with fatal and nonfatal outcome. (C) Correlation of TNF-a serum expression with SNP1 genotypes in hospitalized SFTS patients in acute phase. Compared to the TT carriers, the <i>C</i> allele carriers had had a comparable TNF-a serum expression (<i>P</i> = 0.096). (D) Correlation of TNF-a serum expression with SNP5 genotypes in hospitalized SFTS patients in acute phase. Compared to the GG carriers, the <i>A</i> allele carriers had a markedly lower TNF-a serum expression (<i>P</i> = 0.01).