Additional file 6: of Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer

Fold-change consistency between EdgeR and DESeq2 methods. A) Correlation analysis between fold-change obtained by both methods. The figure shows a tight linear trend between EdgeR and DESeq2 fold-change estimations. Genes found significant for both methods are represented in yellow circles, in green and red are genes significantly differentially expressed by one of the two methods and in white, genes with no significant changes by both techniques. B) Bland Altman analysis comparing the mean fold-changes of both methods (x-axis) and the difference between them (y-axis). This plot allows the identification of any systematic difference between methods and possible outliers. Each circle represents an HSP gene and their colours the subtype for which the fold-change was calculated. The blue dotted line represents the mean difference between both techniques (0.02) and the light blue dashed line depicts the upper (0.88) and lower (− 0.84) limits of the 95% confidence interval of the differences. (PDF 175 kb