<p>(A and B) After relevant treatment, mice were anesthetized, intubated and connected to mechanical ventilator and airways responsiveness to nebulized increasing dose of methacholine was determined. (D) mice with COPD phenotype show higher airway resistance at baseline. Data represent mean and SEM calculated from 6 animals (* p≤0.05, different from respective sham, Two-way ANOVA; # p≤0.05, different from normal sham, ANOVA).</p
<p>. (A) Enhanced pause (Penh) in response to 15 mg/ml of methacholine was measured in A/J, C57BL/6J...
<p>(A) Log<sub>2</sub>(Penh) response curve to increasing doses of methacholine in A/J, C57BL/6J, Bc...
Corticosteroid resistance is a major barrier to the effective treatment of chronic obstructive pulmo...
<p>Cytospins of CD45+ cells isolated from lung digests of sham- or RV-infected mice were stained wit...
<p>H & E-stained lung sections from RV-infected mice with COPD phenotype maintained on quercetin con...
<div><p>Acute exacerbations are the major cause of morbidity and mortality in patients with chronic ...
Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstruct...
Chronic obstructive pulmonary disease (COPD) is the major cause of morbidity and mortality worldwide...
Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchi...
<p>Supernatants from lung homogenates of sham or RV infected normal and COPD mice were used for dete...
<p>Airway resistance curves to methacholine for (A) WT and (B) PHIL mice; (C) Maximal airway resista...
<p>After last OVA challenge, mice were exposed to a series of incremental dosages of methacholine (6...
<p>AHR was measured using plethysmography 24 h after the final OVA challenge, in mice given various ...
<p>The airway resistance (R), after increasing concentrations of methacholine (0–10 mg/ml), was meas...
<p>To determine bronchial hyperresponsiveness, lung function analysis was performed using the IPL an...
<p>. (A) Enhanced pause (Penh) in response to 15 mg/ml of methacholine was measured in A/J, C57BL/6J...
<p>(A) Log<sub>2</sub>(Penh) response curve to increasing doses of methacholine in A/J, C57BL/6J, Bc...
Corticosteroid resistance is a major barrier to the effective treatment of chronic obstructive pulmo...
<p>Cytospins of CD45+ cells isolated from lung digests of sham- or RV-infected mice were stained wit...
<p>H & E-stained lung sections from RV-infected mice with COPD phenotype maintained on quercetin con...
<div><p>Acute exacerbations are the major cause of morbidity and mortality in patients with chronic ...
Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstruct...
Chronic obstructive pulmonary disease (COPD) is the major cause of morbidity and mortality worldwide...
Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchi...
<p>Supernatants from lung homogenates of sham or RV infected normal and COPD mice were used for dete...
<p>Airway resistance curves to methacholine for (A) WT and (B) PHIL mice; (C) Maximal airway resista...
<p>After last OVA challenge, mice were exposed to a series of incremental dosages of methacholine (6...
<p>AHR was measured using plethysmography 24 h after the final OVA challenge, in mice given various ...
<p>The airway resistance (R), after increasing concentrations of methacholine (0–10 mg/ml), was meas...
<p>To determine bronchial hyperresponsiveness, lung function analysis was performed using the IPL an...
<p>. (A) Enhanced pause (Penh) in response to 15 mg/ml of methacholine was measured in A/J, C57BL/6J...
<p>(A) Log<sub>2</sub>(Penh) response curve to increasing doses of methacholine in A/J, C57BL/6J, Bc...
Corticosteroid resistance is a major barrier to the effective treatment of chronic obstructive pulmo...