Gene expression analysis unravels differences and similarities between H1 derived HLCs and EDECs.

<p>(A) Heatmap representation of key genes involved in hepatic cell fate decision making or characteristic for either hepatocytes (yellow) or cholangiocytes (orange). (B) Venn diagram illustrating the numbers of genes which were expressed either by only one cell type or shared between the cell types. (C) Gene Ontology (GO) analysis of genes expressed only in HLCs (yellow) or in EDECs (with or without Notch inhibition, orange) Shown are pre-selected, significant GO-Terms, for full data set see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200416#pone.0200416.s008" target="_blank">S4</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200416#pone.0200416.s009" target="_blank">S5</a> Tables.