Unembryonated <i>T</i>. <i>muris</i> eggs treated with diaminothienopyrimidines have altered embryonation.

<p>Unembyronated eggs were soaked in 100 μM compound (unless specified otherwise) at 26°C (unless specified otherwise) for the duration of the embryonation process (56–60 days) and then embryonation determined and eggs imaged using an Olympus BX63 microscope. Scale bar indicates 10 μm. <b>(a)</b> Typical embryonated egg and <b>(b)</b> unembryonated egg. <b>(c)</b> treatment with DATPs increased the incidence of unembryonated eggs. Representative pictures of <b>(d)</b> DMSO, <b>(e) OX02925</b>, <b>(f) OX02926</b>, <b>(g) OX03143</b> and <b>(h) OX03147</b> 100 μM and <b>(i) OX03147</b> 1 μM soaked <i>T</i>. <i>muris</i> eggs. <b>(j)</b> Unembyronated eggs soaked in <b>OX03147</b> at room temperature for 56 days and embryonation determined. <b>(k)</b> Unembyronated eggs soaked in <b>OX03147</b> at 26°C for 56 days and larval length calculated using ImageJ.