Strain-dependent role of capsular polysaccharide in interference of <i>S</i>. <i>suis</i> serotype 2-induced cytokine production by dendritic cells (DCs).

<p>Cytokine production by DCs following infection with wild-type and non-encapsulated mutant strains after 16 h of incubation, as measured by ELISA, with the exception of IFN-β, after 6 h of incubation, by RT-qPCR. Production of TNF (A), IL-6 (B), IL-12p70 (C), CXCL1 (D), and IFN-β (E). Data represent the mean ± SEM from four independent experiments. C- denotes the negative control (cells in medium alone). *** (<i>p</i> < 0.001) indicates a significant difference between P1/7 and P1/<i>7</i>Δ<i>cpsF</i> or P1/<i>7</i>Δ<i>neuC</i>.