Additional file 10: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Additional file 12: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S4. (A and B) Real-time PCR of NANOG, BMI-1, SOX2 and OCT4 in the indicated cells. Transcript...

Additional file 13: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S5. (A-C) Real-time PCR of BCL2, BCL-xL, Survivin and Mcl-1 in the indicated cells. Transcrip...

Additional file 4: Figure S1. of Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

Dong Ren (135842)
Qing Yang (67856)
Yuhu Dai (436301)
Wei Guo (86150)
Hong Du (117108)
Libing Song (203669)
Xinsheng Peng (350750)

July 2017

miR-210-3p expression is upregulated in bone metastatic PCa tissues and cells. (a) Percentages and n...

Additional file 9: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S7. Univariate and multivariate analysis of factors associated with overall survival in 245 pa...

Additional file 3: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S3. The basic information of 20 paired prostate adenocarcinoma patients for miR-133a-3p expres...

Additional file 5: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S5. The basic information of 245 prostate adenocarcinoma patients for miR-133a-3p expression a...

Additional file 4: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S4. The basic information of 48 patients with benign prostate lesions for miR-133a-3p expressi...

Additional file 15: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S7. (A-C) ELISA analysis of EGF, bFGF, IGF1, IGF2, NGF and HGF concentration in the supernata...

Additional file 14: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S6. Predicted miR-133a-3p targeting sequence and mutant sequences in 3â˛UTRs of EGFR, FGFR1,...

Additional file 2: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S2. A list of primers used in the reactions for real-time RT-PCR. (PDF 60Â kb

Additional file 8: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S2. Low expression of miR-133a-3p correlates with poor clinicopathological characteristics an...

Additional file 4: Table S4. of Downregulation of miR-141-3p promotes bone metastasis via activating NF-ÎşB signaling in prostate cancer

Shuai Huang (60512)
Qingde Wa (4641736)
Jincheng Pan (461203)
Xinsheng Peng (350750)
Dong Ren (135842)
Yan Huang (46805)
Xiao Chen (260187)
Yubo Tang (350759)

December 2017

The relationship between miR-141-3p and clinicopathological characteristics in 141 patients with pro...

Additional file 6: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S1. miR-133a-3p is downregulated in PCa tissues. (A) miR-133a-3p expression levels was decrea...

Additional file 11: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S3. Real-time PCR analysis of miR-133a-3p expression in the indicated PC-3, C4-2B and VCaP ce...

Additional file 16: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S8. AKT signaling was essential for the pro-tumor roles of silencing miR-133a-3p in PCa cells...

Additional file 12: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S4. (A and B) Real-time PCR of NANOG, BMI-1, SOX2 and OCT4 in the indicated cells. Transcript...

Additional file 13: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S5. (A-C) Real-time PCR of BCL2, BCL-xL, Survivin and Mcl-1 in the indicated cells. Transcrip...

Additional file 4: Figure S1. of Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

Dong Ren (135842)
Qing Yang (67856)
Yuhu Dai (436301)
Wei Guo (86150)
Hong Du (117108)
Libing Song (203669)
Xinsheng Peng (350750)

July 2017

miR-210-3p expression is upregulated in bone metastatic PCa tissues and cells. (a) Percentages and n...

Additional file 9: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S7. Univariate and multivariate analysis of factors associated with overall survival in 245 pa...

Additional file 3: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S3. The basic information of 20 paired prostate adenocarcinoma patients for miR-133a-3p expres...

Additional file 5: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S5. The basic information of 245 prostate adenocarcinoma patients for miR-133a-3p expression a...

Additional file 4: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S4. The basic information of 48 patients with benign prostate lesions for miR-133a-3p expressi...

Additional file 15: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S7. (A-C) ELISA analysis of EGF, bFGF, IGF1, IGF2, NGF and HGF concentration in the supernata...

Additional file 14: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S6. Predicted miR-133a-3p targeting sequence and mutant sequences in 3â˛UTRs of EGFR, FGFR1,...

Additional file 2: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Table S2. A list of primers used in the reactions for real-time RT-PCR. (PDF 60Â kb

Additional file 8: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S2. Low expression of miR-133a-3p correlates with poor clinicopathological characteristics an...

Additional file 4: Table S4. of Downregulation of miR-141-3p promotes bone metastasis via activating NF-ÎşB signaling in prostate cancer

Shuai Huang (60512)
Qingde Wa (4641736)
Jincheng Pan (461203)
Xinsheng Peng (350750)
Dong Ren (135842)
Yan Huang (46805)
Xiao Chen (260187)
Yubo Tang (350759)

December 2017

The relationship between miR-141-3p and clinicopathological characteristics in 141 patients with pro...

Additional file 6: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S1. miR-133a-3p is downregulated in PCa tissues. (A) miR-133a-3p expression levels was decrea...

Additional file 11: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S3. Real-time PCR analysis of miR-133a-3p expression in the indicated PC-3, C4-2B and VCaP ce...

Additional file 16: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S8. AKT signaling was essential for the pro-tumor roles of silencing miR-133a-3p in PCa cells...

Additional file 12: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S4. (A and B) Real-time PCR of NANOG, BMI-1, SOX2 and OCT4 in the indicated cells. Transcript...

Additional file 13: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Yubo Tang (350759)
Jincheng Pan (461203)
Shuai Huang (60512)
Xinsheng Peng (350750)
Xuenong Zou (291919)
Yongxiang Luo (1492720)
Dong Ren (135842)
Xin Zhang (35492)
Ronggang Li (4399720)
Peiheng He (5534342)
Qingde Wa (4641736)

July 2018

Figure S5. (A-C) Real-time PCR of BCL2, BCL-xL, Survivin and Mcl-1 in the indicated cells. Transcrip...

Additional file 4: Figure S1. of Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

Dong Ren (135842)
Qing Yang (67856)
Yuhu Dai (436301)
Wei Guo (86150)
Hong Du (117108)
Libing Song (203669)
Xinsheng Peng (350750)

July 2017

miR-210-3p expression is upregulated in bone metastatic PCa tissues and cells. (a) Percentages and n...

Additional file 10: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Abstract

Extracted data

Additional file 10: of Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Abstract

Extracted data

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