<p>Formyl glycals are the versatile synthetic intermediates and can serves as precursor for the synthesis of various C and N-nucleosides. Due to the presence of electron donating and electron withdrawing character on formyl sugars which makes the molecule more susceptible to nucleophilic attack. Utilizing same strategy, we propose the synthesis of diversified C-nucleosides (3-14) by reaction with N,N dinucleophiles. These nucleoside analogs were than tested against viral, bacterial and fungal strains.</p
Nucleoside analogs may participate and interfere in some way with DNA or RNA replication, transcript...
Many nucleosides bearing a carboxylic acid derivative meta- to the site of glycosylation have been s...
A series of doubly flexible nucleoside analogues were designed based on the acyclic sugar scaffold o...
Formyl glycals are the versatile synthetic intermediates and can serves as precursor for the synthes...
Studies on synthesis and biological activity of modified nucleoside and nucleotide analogues have be...
Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents...
The privileged uptake of nucleosides into cells has generated interest in the development of nucleos...
Among the plethora of synthesized compounds, a number of different analogs have shown interesting ac...
International audienceThe structurally unique "fleximer" nucleosides were originally designed to inv...
The alpha- and beta-D-lyxofuranosyl analogues of the naturally occurring nucleosides have been synth...
In the last two years, nucleosides analogues, a class of well-established bioactive compounds, have ...
Formycin is a naturally occurring C-glycoside (C-nucleoside) that possesses antitumor, antibacterial...
[Figure not available: see fulltext.] The minireview surveys the modification of native nucleosides ...
Influenza virus fluAH1N1 still remains a target for its inhibition with smallmolecules. Fleeting nit...
The 2'-N-formamide derivatives of adenosine, cytidine, and 9-beta-D-arabinofuranosyladenine were syn...
Nucleoside analogs may participate and interfere in some way with DNA or RNA replication, transcript...
Many nucleosides bearing a carboxylic acid derivative meta- to the site of glycosylation have been s...
A series of doubly flexible nucleoside analogues were designed based on the acyclic sugar scaffold o...
Formyl glycals are the versatile synthetic intermediates and can serves as precursor for the synthes...
Studies on synthesis and biological activity of modified nucleoside and nucleotide analogues have be...
Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents...
The privileged uptake of nucleosides into cells has generated interest in the development of nucleos...
Among the plethora of synthesized compounds, a number of different analogs have shown interesting ac...
International audienceThe structurally unique "fleximer" nucleosides were originally designed to inv...
The alpha- and beta-D-lyxofuranosyl analogues of the naturally occurring nucleosides have been synth...
In the last two years, nucleosides analogues, a class of well-established bioactive compounds, have ...
Formycin is a naturally occurring C-glycoside (C-nucleoside) that possesses antitumor, antibacterial...
[Figure not available: see fulltext.] The minireview surveys the modification of native nucleosides ...
Influenza virus fluAH1N1 still remains a target for its inhibition with smallmolecules. Fleeting nit...
The 2'-N-formamide derivatives of adenosine, cytidine, and 9-beta-D-arabinofuranosyladenine were syn...
Nucleoside analogs may participate and interfere in some way with DNA or RNA replication, transcript...
Many nucleosides bearing a carboxylic acid derivative meta- to the site of glycosylation have been s...
A series of doubly flexible nucleoside analogues were designed based on the acyclic sugar scaffold o...