Microfilament bundles in <i>ced-1</i> apoptotic cells.

<p>(A-C) TEM micrographs of <i>ced-1(e1735)</i> apoptotic cells showing microfilament bundles. The plasma membrane (yellow arrowhead) and the nuclear envelope (white arrowhead) of the apoptotic cell are indicated in all panels. (A) Example of a single bundle; a higher magnification of the boxed region is shown in panel A’, and indicates a single microfilament (open arrows) and two MTs (open arrowheads). (B and B’) Apoptotic cell with multiple microfilament bundles (green arrows), visible as cross sections; note that the surface of the cell is relatively smooth. (C and C’) Older apoptotic cell, as indicated by the convoluted nuclear membrane and increased cytoplasmic density. Note that the surface has bumps or ridges overlying each of the microfilament bundles. Bar = 200 nm (A), 50 nm (A’), 1 micron (B,C); 0.5 micron (B’, C’).