MOESM4 of Cell surface ectodomain integrity of a subset of functional HIV-1 envelopes is dependent on a conserved hydrophilic domain containing region in their C-terminal tail

Additional file 4: Fig. S3. Infectivity and neutralization assays of JRCSF and JRCSFΔCT pseudoviruses. (a) Infectivity of JRCSF Env wild type and JRCSFΔCT mutant pseudoviruses using TZM-bl reporter based cell assay. (b) IC50 values of JRCSF wild type and JRCSFΔCT mutant pseudoviruses with the cleavage non-specific bNAb VRC01, glycan-dependent and conformational bNAb PG9, PGT121, trimer-selective and cleavage-specific bNAbs PGT151 and PGT145, MPER-directed bNAbs 10E8 and non-NAbs F105 and 17b