Effects of cytokine stimulation on CD98 expression: Samples were compared using Wilcoxon matched-pairs signed rank tests and multiplicity was controlled for by FDR testing.

<p>Bars indicate the median, significance was defined as p≤0.05 (*). A. Representative histograms of CD98 expression on unstimulated and stimulated CD56^bright CXCR6⁺ (I, grey: unstimulated; purple: stimulated), CD56^dim CXCR6⁺ (II, grey: unstimulated; teal: stimulated), CD56^bright CXCR6^- (III, grey: unstimulated; purple: stimulated) and CD56^dim CXCR6^- (IV, grey: unstimulated; teal: stimulated) NK cells from blood (left), liver (middle) and spleen (right) samples. B. Expression (MdFI) of CD98 on unstimulated (grey) and CD56^brightCD16^- (purple) and CD56^dimCD16⁺ (teal) tissue-resident (TR), tissue-derived (TD) and peripheral blood (PB) NK cells from paired liver-blood (left diagram, n = 12) and spleen-blood (right diagram, n = 11) samples.