Characteristics of liver tissue upon different weight loss interventions.

<p>Relative liver weight (n = 11–15 per group) (a) Serum alanine aminotransferase (ALT) levels (n = 6–9 per group) (b) and hepatic triglyceride (TG) content (n = 6 per group) (c). H&E stained sections of liver tissue from LEAN (d), R-NC (e), R-HF (f) and OBESE (g) mice (magnification 10x, scale bars indicate 200μm). Steatosis (h), Inflammatory activity (i) and Fibrosis (j) score and Relative frequency of liver disease (n = 11–15 per group) (k); Relative mRNA expression levels of TNF-alpha (n = 6–8 per group) (l). Data are presented as mean±SEM. * P<0.05; *** P<0.001.