NFATc1 expression (MFI) in the total study population of TAC-treated patients.

<p>Unstimulated (<i>grey</i>) and PMA/ionomycin stimulated (<i>white</i>) blood samples were stained for the expression of NFATc1 in CD3⁺ (<i>upper left graph</i>), CD4⁺ (<i>upper middle graph</i>), CD8⁺ (<i>upper right graph</i>), CD4⁺CD28⁺ (<i>lower left graph</i>), CD8⁺CD28⁺ (<i>lower middle graph</i>) and CD8⁺CD28^- (<i>lower right graph</i>) T cells. Data are plotted as box and whiskers (Tukey style); n = 23 isotype controls, n = 10 healthy controls, n = 11 TAC patients before transplantation; *) p < 0.05, **) p < 0.01, ***) p < 0.001.