The cell-free H₂O₂/LPO/(SCN^-/I^-) system inactivates A/Swine/Illinois/02860/2009 H1N2 influenza A virus.

<p>The antiviral action of the cell-free H₂O₂/LPO/(SCN^-/I^-) system was tested against the A/Swine/Illinois/02860/2009 (H1N2) influenza A virus. Viruses were incubated in the presence or absence of the components of the cell-free system as indicated for 1 hour when (A) SCN^- or (B) I^- was used as LPO substrate. Viral inactivation was assessed by plate-forming unit assay using MDCK cells. Mean+/-S.E.M., n = 4–5. (C) SCN^- and I^- dose-dependence of A/Swine/Illinois/02860/2009 inactivation. Mean+/-S.E.M., n = 3. One-way ANOVA, Tukey’ multiple comparison test. Ns, non-significant, **, p<0.01; ***, p<0.001. SCN^-, thiocyanate; OSCN^-, hypothiocyanite; I^-, iodide; OI^-, hypoiodite; LPO, lactoperoxidase; GO, glucose oxidase; MDCK, Madin-Darby canine kidney cells; PFU, plaque-forming unit.