TCRβ expression correlates with enhanced phagocytosis of parasites by macrophages.

<p><i>A</i>: Splenocytes and parasitized red blood cells (pRBCs) were isolated from C57BL/6 mice on day 3 post-infection with <i>Plasmodium berghei</i> ANKA. A 1:1 ratio of splenocytes (labeled with macrophage and T lymphocyte markers) and pRBCs (labeled with CellTrace^®) were then incubated for 90 minutes to assess the effect of TCRβ expression by Ly6G⁻CD11b^highF4/80⁺ macrophages on phagocytosis in an <i>in vitro</i> assay. <i>B</i>: Expression of TCRβ correlates with enhanced phagocytosis of pRBCs by macrophages. n = 3 for each phagocytosis assay. Results are presented as mean ± standard deviation and are a replicate of three independent experiments. Significant difference between TCRβ⁺ versus TCRβ⁻ macrophages is indicated as **P < 0.01. P−value was calculated using the Mann Whitney <i>U</i> test.