<p>(A) The holding potential (V<sub>h</sub>) was set at ─90 mV, and the test potentials increased from ─70 mV to 50 mV in 10 mV steps to obtain the I<sub>CaL</sub> current amplitude (B) Simulated (solid line) normalized I–V relationship of I<sub>CaL</sub> and experimental (filled triangle) I–V data. (C) The holding potential (V<sub>h</sub>) was set at ─90 mV,and the test potentials stepped from ─70 mV to 50 mV in 20 mV steps to obtain the I<sub>CaT</sub> current amplitude. (D) Simulated (solid line) normalized I–V relationship of I<sub>CaT</sub> and experimental (filled triangle) I–V data [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200712#pone.0200712.ref056" target="_blank">56</a>].</p
International audienceWe present a smooth muscle model which enables the simulation of its contracti...
<p>(A) Inactivation of I<sub>Kv1</sub> is illustrated in whole-cell currents elicited by 15s depolar...
<p><b>Comparison of experimental & simulated spike-type APs of two different shapes produced by syna...
<p><b>Effects of inhibiting the inward currents I</b><sub><b><i>CaT</i></b></sub><b>and I</b><sub><b...
Urinary incontinence is associated with enhanced spontaneous phasic contractions of the detrusor smo...
The complex model of the lower part of the urinary tract is introduced. It consists of the detrusor ...
Urinary incontinence is associated with enhanced spontaneous phasic contractions of the detrusor smo...
<p>The solid red line and solid blue line represent the simulated [Ca]<sub>i</sub> and [Ca]<sub>MT</...
International audienceThis paper presents an original smooth muscle model based on the Huxley micros...
Certain smooth muscles, such as the detrusor of the urinary bladder, exhibit a variety of spikes tha...
Background and hypothesis Detrusor smooth muscle cells (DSMCs) of the urinary bladder are electrical...
International audienceWe present here a major update of our smooth muscle model. It's aim is to enab...
Detrusor smooth muscle cells (DSMCs) of the urinary bladder are electrically connected to one anothe...
International audienceWe present a new model of smooth muscle that can be used to simulate the effec...
<p>Amplification of the observed sEJP (solid lower trace, blue) to estimate the sEJP underlying AP. ...
International audienceWe present a smooth muscle model which enables the simulation of its contracti...
<p>(A) Inactivation of I<sub>Kv1</sub> is illustrated in whole-cell currents elicited by 15s depolar...
<p><b>Comparison of experimental & simulated spike-type APs of two different shapes produced by syna...
<p><b>Effects of inhibiting the inward currents I</b><sub><b><i>CaT</i></b></sub><b>and I</b><sub><b...
Urinary incontinence is associated with enhanced spontaneous phasic contractions of the detrusor smo...
The complex model of the lower part of the urinary tract is introduced. It consists of the detrusor ...
Urinary incontinence is associated with enhanced spontaneous phasic contractions of the detrusor smo...
<p>The solid red line and solid blue line represent the simulated [Ca]<sub>i</sub> and [Ca]<sub>MT</...
International audienceThis paper presents an original smooth muscle model based on the Huxley micros...
Certain smooth muscles, such as the detrusor of the urinary bladder, exhibit a variety of spikes tha...
Background and hypothesis Detrusor smooth muscle cells (DSMCs) of the urinary bladder are electrical...
International audienceWe present here a major update of our smooth muscle model. It's aim is to enab...
Detrusor smooth muscle cells (DSMCs) of the urinary bladder are electrically connected to one anothe...
International audienceWe present a new model of smooth muscle that can be used to simulate the effec...
<p>Amplification of the observed sEJP (solid lower trace, blue) to estimate the sEJP underlying AP. ...
International audienceWe present a smooth muscle model which enables the simulation of its contracti...
<p>(A) Inactivation of I<sub>Kv1</sub> is illustrated in whole-cell currents elicited by 15s depolar...
<p><b>Comparison of experimental & simulated spike-type APs of two different shapes produced by syna...