<div><p>Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and reactants involved in certain metabolic pathways in bacteria. Motivated by microcompartment assembly, we use coarse-grained computational and theoretical modeling to study the factors that control the size and morphology of a protein shell assembling around hundreds to thousands of molecules. We perform dynamical simulations of shell assembly in the presence and absence of cargo over a range of interaction strengths, subunit and cargo stoichiometries, and the shell spontaneous curvature. Depending on these parameters, we find that the presence of a cargo can either increase or decrease the size of a shell relative to its intrinsic spon...
Bacterial microcompartments (BMCs) are organelles composed of a selectively permeable protein shell ...
Bacterial microcompartments (BMCs) are self-assembling prokaryotic organelles consisting of a polyhe...
The use of bacterial production could improve commercial feasibility for biochemicals such as pharma...
Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and r...
Bacterial microcompartments (BMC) are complex macromolecular assemblies that participate to varied c...
Bacterial microcompartments (BMCs) are organelles composed of a selectively permeable protein shell ...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Bacterial microcompartments (BMCs) are polyhedral, protein-based organelles present in a wide range ...
Bacterial microcompartments, or MCPs, are supramolecular structures analogous to eukaryotic organell...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an enzymatic core ...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Despite the vast array of enzymatic activities available to metabolic engineers, many biosyntheses a...
Bacterial microcompartments (BMCs) are organelles composed of a selectively permeable protein shell ...
Bacterial microcompartments (BMCs) are self-assembling prokaryotic organelles consisting of a polyhe...
The use of bacterial production could improve commercial feasibility for biochemicals such as pharma...
Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and r...
Bacterial microcompartments (BMC) are complex macromolecular assemblies that participate to varied c...
Bacterial microcompartments (BMCs) are organelles composed of a selectively permeable protein shell ...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Bacterial microcompartments (BMCs) are polyhedral, protein-based organelles present in a wide range ...
Bacterial microcompartments, or MCPs, are supramolecular structures analogous to eukaryotic organell...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an enzymatic core ...
Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, t...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Despite the vast array of enzymatic activities available to metabolic engineers, many biosyntheses a...
Bacterial microcompartments (BMCs) are organelles composed of a selectively permeable protein shell ...
Bacterial microcompartments (BMCs) are self-assembling prokaryotic organelles consisting of a polyhe...
The use of bacterial production could improve commercial feasibility for biochemicals such as pharma...