MOESM13 of CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

Additional file 13: Fig. S10 . TF motifs explain nature of Independent site activation in absence of CRX. a Heatmap shows unsupervised clustering of [−log10] transformed p-values representing the significance of representation of the noted TF motif within the set of sites. (* -****) represent TFs referenced in details in the text. b Quantification of MEF2D ChIP-seq data at Group C enhancer sites displays loss of signal specifically at Dependent sites (red) in the Crx−/−. Independent sites (blue) show no change in signal. Quantifications of CTCF binding over time (c maximum peak intensity over development and d relative to CRX bindings site at P21) display consistent signal at Group D Independent sites