Adjusted HRs for acute pancreatitis by RPG.

<p>RPG levels for participants without previously diagnosed diabetes at baseline were classified as ≤4.4 (reference), 4.5 to <5.6, 5.6 to <7.8, and ≥7.8 mmol/L. RPG was missing in 8,156 participants. Model was stratified by sex and region and adjusted for age at baseline, education, smoking, alcohol, medication (aspirin, ACE-I, beta blockers, statins, diuretics, Ca⁺⁺ antagonists, metformin, and insulin), and fasting time. Time since birth was used as the underlying time scale with delayed entry at age at baseline. HRs were plotted against the mean level in each adiposity group. Log-scale was used for the y-axis. The squares represent HRs, and the vertical lines represent 95% CIs. The area of the squares is inversely proportional to the variance of the log HRs. The numbers above the vertical lines are point estimates for HRs, and the numbers below the lines are numbers of events. There was evidence that the association of acute pancreatitis risk with RPG deviated from linearity (<i>p</i> = 0.001). The adjusted HR per 1 mmol/L higher RPG was 1.04 (1.02–1.07) (<i>p</i> < 0.001). ACE-I, angiotensin-converting enzyme inhibitor; HR, hazard ratio; RPG, random plasma glucose.