Additional file 1: of Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: the GOMAP study

Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: the GOMAP study. Description of survey flow. Diagnostic assessment of T2D and psychiatric disease. Physical assessments. Table S1. T2D occurrence based on simple logistic regression modelling among patients with SCZ. Figure S1. Manhattan plot of association results from a GWAS on T2D in individuals receiving a combination of three or more psychotropic drugs, including one FGA and one SGA. For each of the 9,565,382 analysed variants the –log10 of the p-value is plotted against its chromosomal position. Blue and red lines indicate suggestive (p < 5*10− 6) and genome-wide (p < 5*10− 8) significance. Figure S2. Quantile-quantile plot of association results from a GWAS on T2D in individuals receiving a combination of three or more psychotropic drugs, including one FGA and one SGA. For each SNP the –log10 of the p-value is plotted against its expected value under the null distribution. (DOCX 219 kb