<p>Representative graphs of 6 different tumor samples showing relative <i>DNMT3B7</i> expression, as measured by reads per kilobase per million (RPKM) or RNA-Seq by Expectation Maximization (RSEM), in unmatched normal and tumor tissues in (A) HNSC, (B) UCEC, and (C) THCA. Expression of <i>DNMT3B7</i> in matched patient samples is shown in (D) LIHC and (E) LUAD. <i>DNMT3B7</i> expression in primary and recurrent tissues in (F) LGG (<i>p</i> = 0.005) was assessed when normal samples were not available. All samples shown here were significant, <i>p</i> < 0.001, unless otherwise stated.</p
<p>Three distinct samples from patient-matched normal (N1-3) and tumour (T1-3) tissues were analysed...
<p>Box plots of expression levels of six miRNAs in both tumors and paired normal tissues. The relati...
a<p>Spearman’s coefficient of correlation;</p>b<p><i>P</i>-value obtained from Spearman’s correlatio...
<p>The median <i>DNMT3B7</i> expression for each individual tumor was determined to divide patients ...
<p><i>DNMT3B7</i> reads per kilobase per million (RPKM) values of A) normal tissue versus primary tu...
<p>(A) Array Northern analysis of DNMT3B mRNA expression on Affymetrix HGU133Plus2.0 arrays in tumor...
<p>cDNA was synthesized from amplified RNA purified from tumor tissue ob...
A-D) Log2-transformed (A,B, and D) or raw (C) RSEM values of SFs gene-expression levels (n = 58 matc...
<p>A. Levels of DNMT1 and DNMT3b were examined in cancer (CA) and non-malignant tissue (NT) by Weste...
Cancer cells are known for aberrant methylation patterns leading to altered gene expression and tumo...
<p>(A) Displayed are differences in nuclear expression, measured as the percentage of positively sta...
Reproducibility of within-donor biological replicates (average of three technical replicates each) o...
<p>Determination of DNMT activity in mammary gland <b>(a)</b> and tumors <b>(b)</b> from all experim...
<p>Normalized gene expression (CT-values) of 44 genes expressed in ≥50% of tumor samples per metasta...
<p>Relative NNMT expression levels were determined in 7 human cancer cell lines. ΔCt values indicate...
<p>Three distinct samples from patient-matched normal (N1-3) and tumour (T1-3) tissues were analysed...
<p>Box plots of expression levels of six miRNAs in both tumors and paired normal tissues. The relati...
a<p>Spearman’s coefficient of correlation;</p>b<p><i>P</i>-value obtained from Spearman’s correlatio...
<p>The median <i>DNMT3B7</i> expression for each individual tumor was determined to divide patients ...
<p><i>DNMT3B7</i> reads per kilobase per million (RPKM) values of A) normal tissue versus primary tu...
<p>(A) Array Northern analysis of DNMT3B mRNA expression on Affymetrix HGU133Plus2.0 arrays in tumor...
<p>cDNA was synthesized from amplified RNA purified from tumor tissue ob...
A-D) Log2-transformed (A,B, and D) or raw (C) RSEM values of SFs gene-expression levels (n = 58 matc...
<p>A. Levels of DNMT1 and DNMT3b were examined in cancer (CA) and non-malignant tissue (NT) by Weste...
Cancer cells are known for aberrant methylation patterns leading to altered gene expression and tumo...
<p>(A) Displayed are differences in nuclear expression, measured as the percentage of positively sta...
Reproducibility of within-donor biological replicates (average of three technical replicates each) o...
<p>Determination of DNMT activity in mammary gland <b>(a)</b> and tumors <b>(b)</b> from all experim...
<p>Normalized gene expression (CT-values) of 44 genes expressed in ≥50% of tumor samples per metasta...
<p>Relative NNMT expression levels were determined in 7 human cancer cell lines. ΔCt values indicate...
<p>Three distinct samples from patient-matched normal (N1-3) and tumour (T1-3) tissues were analysed...
<p>Box plots of expression levels of six miRNAs in both tumors and paired normal tissues. The relati...
a<p>Spearman’s coefficient of correlation;</p>b<p><i>P</i>-value obtained from Spearman’s correlatio...