<p>A: Immunostaining of the macrophage marker F4/80 (brown) in adipose tissue (scale bar = 100 μM). B: mRNA levels of the macrophage marker, <i>F4/80</i> and <i>CD11c</i>, tumor necrosis factor α (<i>TNF</i>α), monocyte chemoattractant protein-1 (<i>Mcp-1</i>), Forkhead Boxprotein P3 <i>(Foxp3</i>), and adiponectin in adipose tissue. All mRNA expression data were normalized to <i>36B4</i>. C: Immunofluorescence staining for DAPI (blue), F4/80 (red) and TNFα (green) in adipose tissue (scale bar, 100 μm). * <i>p</i> < 0.05. n.s. = not significant.</p
<p>(a) <i>Tnfα</i>, <i>F4/80</i>, and <i>Il6</i> mRNA expression in the epididymal adipose tissue SV...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a) Bodyweight development upon LFD ...
(A) Quantification of CD45 staining for leukocytes of EpAT (n = 16 for HFD and n = 7 for SFD). (B) Q...
<p>(<b>A</b>) Light micrographs (×10 magnification) of H&E stained slides of WAT from f/f and KO mic...
<p>A: mRNA levels of thermogenic and beige adipocyte marker genes in the inguinal adipose tissue fro...
<p>A) Lack of high-fat diet-associated macrophage ‘crown-like structures’ in visceral adipose tissue...
<p>(<b>A</b>) Quantitative real-time PCR analysis of adipose tissue (epididymal fat pad) of <i>IL-1b...
<p>Periogonadal adipose tissue mRNA levels of (A) TNFα, IL-6, and CCL2 and (B) F4/80, CD68, CD11b, C...
<p>Relative mRNA expression of macrophage and inflammatory markers in epididymal fat tissue from WT ...
<p>(A) Representative images of hematoxylin-eosin staining (original magnification x40, scale bar = ...
<p>Real-time RT-PCR analysis of (A) brown adipose tissue (BAT) and (B) subcutaneous white adipose ti...
<p>(A) FACS detection of M1-type, F4/80+CD11b+CD11c+ pro-inflammatory macrophages in adipose tissue ...
<p>After 16 weeks of low fat diet (LFD) or high fat diet (HFD) intervention, adipose tissue of wild-...
<p>Mouse cytokine profiler analysis in pooled plasma: (A) Data are expressed as mean±SEM of n = 8 Ct...
<p>A) Macrophages in crown-like structures (CLS) were identified by immunohistochemical staining wit...
<p>(a) <i>Tnfα</i>, <i>F4/80</i>, and <i>Il6</i> mRNA expression in the epididymal adipose tissue SV...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a) Bodyweight development upon LFD ...
(A) Quantification of CD45 staining for leukocytes of EpAT (n = 16 for HFD and n = 7 for SFD). (B) Q...
<p>(<b>A</b>) Light micrographs (×10 magnification) of H&E stained slides of WAT from f/f and KO mic...
<p>A: mRNA levels of thermogenic and beige adipocyte marker genes in the inguinal adipose tissue fro...
<p>A) Lack of high-fat diet-associated macrophage ‘crown-like structures’ in visceral adipose tissue...
<p>(<b>A</b>) Quantitative real-time PCR analysis of adipose tissue (epididymal fat pad) of <i>IL-1b...
<p>Periogonadal adipose tissue mRNA levels of (A) TNFα, IL-6, and CCL2 and (B) F4/80, CD68, CD11b, C...
<p>Relative mRNA expression of macrophage and inflammatory markers in epididymal fat tissue from WT ...
<p>(A) Representative images of hematoxylin-eosin staining (original magnification x40, scale bar = ...
<p>Real-time RT-PCR analysis of (A) brown adipose tissue (BAT) and (B) subcutaneous white adipose ti...
<p>(A) FACS detection of M1-type, F4/80+CD11b+CD11c+ pro-inflammatory macrophages in adipose tissue ...
<p>After 16 weeks of low fat diet (LFD) or high fat diet (HFD) intervention, adipose tissue of wild-...
<p>Mouse cytokine profiler analysis in pooled plasma: (A) Data are expressed as mean±SEM of n = 8 Ct...
<p>A) Macrophages in crown-like structures (CLS) were identified by immunohistochemical staining wit...
<p>(a) <i>Tnfα</i>, <i>F4/80</i>, and <i>Il6</i> mRNA expression in the epididymal adipose tissue SV...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a) Bodyweight development upon LFD ...
(A) Quantification of CD45 staining for leukocytes of EpAT (n = 16 for HFD and n = 7 for SFD). (B) Q...