Hub identification of the networks.

<p>(A) The rankings of each centrality are shown for the dHPC network under the 0.05 threshold. The colored nodes are the upper 25% most central in each metric. (B) The intersections of the upper 25% most central regions of each metric are shown for the dHPC network under the 0.05 threshold. Any region within the overlapping area of at least three metrics was considered a network hub (inside the red perimeter). The hubs were identified in the networks with 0.025 and 0.01 thresholds as well (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006207#pcbi.1006207.s002" target="_blank">S2</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006207#pcbi.1006207.s004" target="_blank">S4</a> Figs), and the hubs of each threshold were intersected (C) to identify stable hubs across the thresholds in each network. Nodes are colored according to the code in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006207#pcbi.1006207.g002" target="_blank">Fig 2</a>.