Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI
- Sadykhov, E.G.
- Pirogov, Yu. A.
- Anisimov, N.V.
- Gulyaev, M .V.
- Pavlovskaya, G. E.
- Meersmann, Thomas
- Belyaev, V.N.
- Fomina, D.V.
- National Research Nuclear University “MEPhI”, Moscow, Russia
- Lomonosov Moscow State University, Moscow, Russia
- Sir Peter Mans eld Imaging Centre, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK
- NIHR Nottingham Biomedical Centre, Nottingham NG7 2RD, UK
Publication date
July 2018
DOI Publisher
Springer Science and Business Media LLCAbstract
Sodium is a key element in a living organism. The increase of its concentration is an indicator of many pathological conditions. 23Na magnetic resonance imaging (MRI) is a quantitative method that allows to determine the sodium content in tissues and organs in vivo. This method has not yet entered clinical practice widely, but it has already been used as a clinical research tool to investigate diseases such as brain tumors, breast cancer, stroke, multiple sclerosis, hypertension, diabetes, ischemic heart disease, osteoarthritis. The active development of the 23Na MRI is promoted by the growth of available magnetic elds, the expansion of hardware capabilities, and the development of pulse sequences with ultra-short echo time
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