DEVELOPMENT OF NEW USEFUL METHODS FOR ALDEHYDE SYNTHESIS AND ITS APPLICATION IN SYNTHESIS

Development of sustainable synthetic technologies for molecular construction is an important but formidably challenging task in modern organic synthesis. Aldehyde synthesis represents a long-standing interest in synthesis because of the synthetic utility. Classic methods for aldehyde synthesis have the drawbacks of the use of harsh reaction conditions, poor atom-economy and multi-step operation, and production of stoichiometric amount of chemical wastes. The state-of-the-art strategies employ transition metal complexes as catalysts to promote formylation reactions. The concerns of catalyst cost, operation complexity and poor functional group tolerance demands more efficient synthetic technologies. My Ph.D. study focuses on design of conceptually novel catalytic systems, invention of reagents and exploration of new reactivities to create unprecedented processes the synthesis of fundamentally important class of chemicals - aldehydes with the emphasis on sustainability, selectivity, practicality and utility