Early embryogenesis relies on the translational regulation of maternally stored mRNAs. In sea urchin, fertilization triggers a dramatic rise in translation activity, necessary for the onset of cell division. Here, the full spectrum of the mRNAs translated upon fertilization was investigated by polysome profiling and sequencing. The translatome of the early sea urchin embryo gave a complete picture of the polysomal recruitment dynamics following fertilization. Our results indicate that only a subset of maternal mRNAs were selectively recruited onto polysomes, with over-represented functional categories in the translated set. The increase in translation upon fertilization depends on the formation of translation initiation complexes following ...
Fully grown oocytes undergo their further development in the absence of transcription. Completion of...
A set of 956 expressed sequence tags derived from 7-hour (mid-cleavage) sea urchin embryos was analy...
AbstractThe mRNA’s cap-binding protein eukaryotic translation initiation factor (eIF)4E is a major t...
Sea urchin early development is a powerful model to study translational regulation under physiologic...
La synthèse protéique est une étape importante de la régulation de l'expression des gènes. Dans beau...
International audienceDuring the first steps of sea urchin development, fertilization elicits a mark...
During the first steps of sea urchin development, fertilization elicits a marked increase in protein...
Translation is a critical step in gene expression regulation. In sea urchin embryos, fertilization i...
International audienceThe large and rapid increase in the rate of protein synthesis following fertil...
International audienceThe cyclin B/CDK1 complex is a key regulator of mitotic entry. Using PP242, a ...
Research on the early development of the sea urchin offers new insights into the process of embryoge...
AbstractSea urchin eggs and early cleavage stage embryos provide an example of regulated gene expres...
Fine tuning of translation for cell cycle dynamics remains an important topic in cell research. Duri...
La régulation fine de la traduction pour la dynamique du cycle cellulaire est un sujet important dan...
International audienceSea urchin eggs and early cleavage stage embryos provide an example of regulat...
Fully grown oocytes undergo their further development in the absence of transcription. Completion of...
A set of 956 expressed sequence tags derived from 7-hour (mid-cleavage) sea urchin embryos was analy...
AbstractThe mRNA’s cap-binding protein eukaryotic translation initiation factor (eIF)4E is a major t...
Sea urchin early development is a powerful model to study translational regulation under physiologic...
La synthèse protéique est une étape importante de la régulation de l'expression des gènes. Dans beau...
International audienceDuring the first steps of sea urchin development, fertilization elicits a mark...
During the first steps of sea urchin development, fertilization elicits a marked increase in protein...
Translation is a critical step in gene expression regulation. In sea urchin embryos, fertilization i...
International audienceThe large and rapid increase in the rate of protein synthesis following fertil...
International audienceThe cyclin B/CDK1 complex is a key regulator of mitotic entry. Using PP242, a ...
Research on the early development of the sea urchin offers new insights into the process of embryoge...
AbstractSea urchin eggs and early cleavage stage embryos provide an example of regulated gene expres...
Fine tuning of translation for cell cycle dynamics remains an important topic in cell research. Duri...
La régulation fine de la traduction pour la dynamique du cycle cellulaire est un sujet important dan...
International audienceSea urchin eggs and early cleavage stage embryos provide an example of regulat...
Fully grown oocytes undergo their further development in the absence of transcription. Completion of...
A set of 956 expressed sequence tags derived from 7-hour (mid-cleavage) sea urchin embryos was analy...
AbstractThe mRNA’s cap-binding protein eukaryotic translation initiation factor (eIF)4E is a major t...