We are interested in the issue of dissolution of certain soluble rocks, and their geomechanical consequences such subsidence, sinkholes, underground collapse. We will focus on gypsum, although the developed method is usable for salt rocks. In this paper, a large-scale Diffuse Interface Model (DIM) is used to describe the evolution of a gypsum cavity formation induced by dissolution. The method is based upon the assumption of a pseudo-component dissolving with a thermodynamic equilibrium boundary condition. A methodology is proposed based on numerical computations with fixed boundaries in order to choose suitable parameters for the DIM model and hence predict the correct dissolution fluxes and surface recession velocity. Additional simulatio...