First Case of Q Fever Endocarditis Involving the Melody(A (R)) Transcatheter Pulmonary Valve in an Afebrile Child

International audienceIn this article we report the first case of Q fever endocarditis in a 13 years old child with a percutaneous pulmonary Melody(A (R)) valve. The patient had a new onset of Melody valve dysfunction associated with the combination of hepatosplenomegaly and pancytopenia but was afebrile. Although blood cultures were negative, we have further investigated in the direction of infective endocarditis by performing PCR detection and the serology of C. burnetii which were positive. A combination antibiotic therapy with doxycycline and hydroxychloroquine was started with good clinical evolution. Our case emphasizes the fact that any Melody valvular dysfuntion should be considered as a potential infective endocarditis despite the absence of typical bacterial features