International audienceThe success of intravenous immunoglobulin immunotherapy in autoimmune diseases has inspired the development of novel Fc-based therapeutics, in particular, multimerized polyvalent Fc molecules. A new study reports that a recombinant IgG1 Fc hexamer alleviates acute and chronic autoimmune diseases in mice
The application of Fc (fragment crystallizable)-based cytokines (the fusion of the constant region o...
We have engineered the Fc region of a human immunoglobulin G (IgG) to generate a mutated antibody th...
Intravenous IgG has been adopted as treatment for various immune-related diseases, including immune ...
International audienceThe success of intravenous immunoglobulin immunotherapy in autoimmune diseases...
High-dose (1-2 g/kg) intravenous immunoglobulin (IVIg), and more recently, subcutaneously delivered ...
Intravenous human immunoglobulin G (IVIG) may have therapeutic benefit in neuromyelitis optica spect...
International audienceNeonatal Fc receptors (FcRns) recycle IgGs by preventing their lysosome degrad...
Multimeric fragment crystallizable (Fc) regions and Fc-fusion proteins are actively being explored a...
Novel molecules that directly target the neonatal Fc receptor (FcRn) and/or Fc gamma receptors (FcγR...
Immunoglobulin G (IgG) mediates pro- and anti-inflammatory activities through the engagement of its ...
Antibody-based therapeutics are a rapidly expanding class of biopharmaceuticals. The number of appro...
Therapeutic use and function of recombinant molecules can be studied by the expression of foreign ge...
Intravenous immunoglobulin (IVIG) is an established treatment for numerous autoimmune conditions. Al...
Abstract Background High-dose intravenous immunoglobu...
Antibodies are Y-shaped proteins that are secreted by B-cells that makes up part of the defence mech...
The application of Fc (fragment crystallizable)-based cytokines (the fusion of the constant region o...
We have engineered the Fc region of a human immunoglobulin G (IgG) to generate a mutated antibody th...
Intravenous IgG has been adopted as treatment for various immune-related diseases, including immune ...
International audienceThe success of intravenous immunoglobulin immunotherapy in autoimmune diseases...
High-dose (1-2 g/kg) intravenous immunoglobulin (IVIg), and more recently, subcutaneously delivered ...
Intravenous human immunoglobulin G (IVIG) may have therapeutic benefit in neuromyelitis optica spect...
International audienceNeonatal Fc receptors (FcRns) recycle IgGs by preventing their lysosome degrad...
Multimeric fragment crystallizable (Fc) regions and Fc-fusion proteins are actively being explored a...
Novel molecules that directly target the neonatal Fc receptor (FcRn) and/or Fc gamma receptors (FcγR...
Immunoglobulin G (IgG) mediates pro- and anti-inflammatory activities through the engagement of its ...
Antibody-based therapeutics are a rapidly expanding class of biopharmaceuticals. The number of appro...
Therapeutic use and function of recombinant molecules can be studied by the expression of foreign ge...
Intravenous immunoglobulin (IVIG) is an established treatment for numerous autoimmune conditions. Al...
Abstract Background High-dose intravenous immunoglobu...
Antibodies are Y-shaped proteins that are secreted by B-cells that makes up part of the defence mech...
The application of Fc (fragment crystallizable)-based cytokines (the fusion of the constant region o...
We have engineered the Fc region of a human immunoglobulin G (IgG) to generate a mutated antibody th...
Intravenous IgG has been adopted as treatment for various immune-related diseases, including immune ...