O impacto da osteoporose no Brasil: dados regionais das fraturas em homens e mulheres adultos - The Brazilian Osteoporosis Study (BRAZOS)

Objectives: The BRAZOS (The Brazilian Osteoporosis Study) study is the first epidemiological and population-based study carried out in a representative sample of Brazilian men and women, 40 years or older, with the objective of identifying the prevalence and main clinical risk factors (CRF) associated with low-impact fractures. This report shows the main results according to each region of the country. Patients and Methods: A total of 2,420 subjects (70% women) from 150 different cities in five geographic regions in Brazil, and from all different socio-economical classes were included in this study. Anthropometrical data, as well life style, previous fractures, nutritional status, physical activity, falls, and quality of life were evaluated by a quantitative individual survey. Low-impact fracture was defined as that resulting from a fall no greater than standing height of an individual. A P < 0.05 was considered significant. Results: Statistically significant differences in the prevalence of fractures among the five Brazilian regions according to gender or social class were not observed. However, in women, a higher incidence of fractures was observed in metropolitan areas than in rural areas, and a tendency for a higher frequency of fractures was observed in men from Northeastern states. Statistically significant differences among men from metropolitan areas or rural areas were not observed. Conclusions: Significant differences in the prevalence of low-impact fractures among the five different regions of Brazil were not observed, as well as its frequency or relevance of risk factors.Wyeth Consumer HealthcareUniv Fed Sao Paulo EPM, Disciplina Reumatol, Sao Paulo, BrazilUniv Sao Paulo, Fac Saude Publ, Dept Nutr, BR-05508 Sao Paulo, BrazilUnifesp EPM, Ctr Paulista Econ Saude, Sao Paulo, BrazilUniv Fed Sao Paulo EPM, Disciplina Reumatol, Sao Paulo, BrazilUnifesp EPM, Ctr Paulista Econ Saude, Sao Paulo, BrazilWeb of Scienc