Myoid hamartomas of the breast - Report of 3 cases and review of the literature

Hamartomas were first described by Albrecht in 1904, who defined them as tumorlike malformations in which there was abnormal blending of the normal components of an organ. The myoid hamartoma is a rare benign lesion of the breast and has an uncertain origin, possibly in the walls of the blood vessels, muscularis mammillae of the areolae, and mainly in myoepithelium. We report 3 cases of myoid hamartomas of the breast, with the clinical, radiologic, and histopathological findings, and review the literature. The 3 lesions showed normal breast ducts and lobules, entrapped by a muscular stroma and some foci of mature adipose tissue. The muscular origin of part of the stroma was confirmed by strong reactiveness with smooth-muscle actin.Univ Fed Sao Paulo, Dept Patol, Escola Paulista Med, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Patol, Escola Paulista Med, Sao Paulo, BrazilWeb of Scienc