Add to ORKGWe have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and correlate it with the allele frequencies at two polymorphic loci (XV-2C and KM-19) closely linked to the cystic fibrosis gene. The DNA came from 193 white Brazilian families affected by cystic fibrosis and living in five different states of Brazil. The distribution of the haplotypes derived from the DF508 and non-DF508 XV-2C/KM-19 genotypes indicates that 88% of the DF508 alleles are linked to haplotype B and suggests that high heterogeneity exists among the non-DF508 cystic fibrosis alleles occurring in different states. Our data can be used to compare linkage disequilibrium between Brazilians and other heterogeneous populations where the D...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator ...
Objective: To verify the presence of δF508 mutation in the cystic fibrosis transmembrane conductance...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
The restriction fragment length polymorphism (RFLP) haplotypes of cystic fibrosis (CF) alleles vary ...
Cystic fibrosis (CF) is an autosomal recessive disease caused by at least 750 different mutations in...
The frequencies of the ΔF508 deletion, the most common cystic fibrosis mutation in Europeans and Eur...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
Blood samples from 44 unrelated cystic fibrosis (CF) patients from Rio de Janeiro, Brazil, were anal...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
The [Delta]F508 mutation in the cystic fibrosis (CF) gene was studied in a population of 18 Brazilia...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator ...
Objective: To verify the presence of δF508 mutation in the cystic fibrosis transmembrane conductance...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
The restriction fragment length polymorphism (RFLP) haplotypes of cystic fibrosis (CF) alleles vary ...
Cystic fibrosis (CF) is an autosomal recessive disease caused by at least 750 different mutations in...
The frequencies of the ΔF508 deletion, the most common cystic fibrosis mutation in Europeans and Eur...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
Blood samples from 44 unrelated cystic fibrosis (CF) patients from Rio de Janeiro, Brazil, were anal...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
The [Delta]F508 mutation in the cystic fibrosis (CF) gene was studied in a population of 18 Brazilia...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator ...
Objective: To verify the presence of δF508 mutation in the cystic fibrosis transmembrane conductance...