The use of Fluor-Hydroxy pulse peel in actinic porokeratosis

BACKGROUND. The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions.(1,2)OBJECTIVE. The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis.METHODS. A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses.RESULTS. Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia. CONCLUSION. The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.Univ Fed Sao Paulo, Escola Paulista Med, Dept Dermatol, Cosmiatry Div, Sao Paulo, BrazilUniv Fed Sao Paulo, Escola Paulista Med, Dept Pathol & Anat, Sao Paulo, BrazilUniv Fed Sao Paulo, Escola Paulista Med, Dept Dermatol, Cosmiatry Div, Sao Paulo, BrazilUniv Fed Sao Paulo, Escola Paulista Med, Dept Pathol & Anat, Sao Paulo, BrazilWeb of Scienc