Add to ORKGAbstract: In spite of considerable evidence on the regulation of immunity by thyroid hormones, the impact of the thyroid status in tumor immunity is poorly understood. Here, we evaluated the antitumor immune responses evoked in mice with different thyroid status (euthyroid, hyperthyroid, and hypothyroid) that developed solid tumors or metastases after inoculation of syngeneic T lymphoma cells. Hyperthyroid mice showed increased tumor growth along with increased expression of cell cycle regulators compared to hypothyroid and control tumor-bearing mice. However, hypothyroid mice showed a higher frequency of metastases than the other groups. Hyperthyroid mice bearing tumors displayed a lower number of tumor-infiltrating T lymphocytes, lower pe...
The association between thyroid cancer and thyroid inflammation has been repeatedly reported and hig...
T helper type 17 (Th17) cells, a newly identified effector T-cell subset, have recently been shown t...
Thyroid hormones are important regulators of cell physiology, inducing cell proliferation, differen...
Abstract: In spite of considerable evidence on the regulation of immunity by thyroid hormones, the i...
The patient’s hormonal context plays a crucial role in the outcome of cancer. However, the associati...
Accumulating evidence indicates a functional crosstalk between immune and endocrine mechanisms in th...
Abstract: We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferat...
Among the many examples of neuroendocrine-immune system interactions the relationship between the th...
Purpose: Hypothyroidism has been shown to induce immunosuppression and both the thyroid status and i...
We reported thyroid hormone (TH) receptor expression in murine dendritic cells (DCs) and 3,5,3'-trii...
The interaction between the immune and the neuroendocrine systems involves, in a bidirectional circu...
Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T ...
BACKGROUND: Papillary thyroid carcinoma (PTC) is frequently accompanied by lymphocytic thyroiditis (...
Abstract: Thyroid hormones (THs) are important regulators of metabolism, differentiation and cell pr...
Background The response of solid tumors such as papillary thyroid cancer (PTC) to immune checkpoint ...
The association between thyroid cancer and thyroid inflammation has been repeatedly reported and hig...
T helper type 17 (Th17) cells, a newly identified effector T-cell subset, have recently been shown t...
Thyroid hormones are important regulators of cell physiology, inducing cell proliferation, differen...
Abstract: In spite of considerable evidence on the regulation of immunity by thyroid hormones, the i...
The patient’s hormonal context plays a crucial role in the outcome of cancer. However, the associati...
Accumulating evidence indicates a functional crosstalk between immune and endocrine mechanisms in th...
Abstract: We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferat...
Among the many examples of neuroendocrine-immune system interactions the relationship between the th...
Purpose: Hypothyroidism has been shown to induce immunosuppression and both the thyroid status and i...
We reported thyroid hormone (TH) receptor expression in murine dendritic cells (DCs) and 3,5,3'-trii...
The interaction between the immune and the neuroendocrine systems involves, in a bidirectional circu...
Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T ...
BACKGROUND: Papillary thyroid carcinoma (PTC) is frequently accompanied by lymphocytic thyroiditis (...
Abstract: Thyroid hormones (THs) are important regulators of metabolism, differentiation and cell pr...
Background The response of solid tumors such as papillary thyroid cancer (PTC) to immune checkpoint ...
The association between thyroid cancer and thyroid inflammation has been repeatedly reported and hig...
T helper type 17 (Th17) cells, a newly identified effector T-cell subset, have recently been shown t...
Thyroid hormones are important regulators of cell physiology, inducing cell proliferation, differen...