Chimaeras are both monsters of the ancient imagination and a long-established research tool. Recent advances, particularly those dealing with the identification and generation of various kinds of stem cells, have broadened the repertoire and utility of mammalian interspecies chimaeras and carved out new paths towards understanding fundamental biology as well as potential clinical applications.National Institutes of Health (U.S.) (Grant HD045022)National Institutes of Health (U.S.) (Grant R37-CA084198)National Institutes of Health (U.S.) (Grant 1R01NS088538-01
Stem cells research is becoming a very interesting field for investigation and experimental studies....
In recent years, there has been an explosion of interest in stem cells, not just within the scientif...
Stem cells (SC) research is an important part of biotechnology that could lead to the development of...
Chimeras are widely acknowledged as the gold standard for assessing stem cell pluripotency, based on...
In this issue of Stem Cell Reports, Hamanaka et al. (2018) describe the generation of chimeric mice ...
j.stem.2007.07.021mera. If the donor tissue and recipient are of different spe-cies, then an intersp...
Gene modification within the murine genome has become a powerful and invaluable tool to investigate ...
Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have...
Contents: Many reports described cell lines derived in domestic species, which presented several imp...
Research on humans is limited, therefore human animal chimeras have been used to study human systems...
The development of human pluripotent stem cells has opened up the possibility to analyse the functio...
All organisms depend on stem cells for their survival. As a result, stem cells may be a prerequisite...
Embryonic pluripotency can be recapitulated in vitro by a spectrum of pluripotent stem cell states s...
The generation of radiation chimeras allows researchers to substitute the hematopoietic system of a ...
The remarkable similarity between non-human primates (NHPs) and humans establishes them as essential...
Stem cells research is becoming a very interesting field for investigation and experimental studies....
In recent years, there has been an explosion of interest in stem cells, not just within the scientif...
Stem cells (SC) research is an important part of biotechnology that could lead to the development of...
Chimeras are widely acknowledged as the gold standard for assessing stem cell pluripotency, based on...
In this issue of Stem Cell Reports, Hamanaka et al. (2018) describe the generation of chimeric mice ...
j.stem.2007.07.021mera. If the donor tissue and recipient are of different spe-cies, then an intersp...
Gene modification within the murine genome has become a powerful and invaluable tool to investigate ...
Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have...
Contents: Many reports described cell lines derived in domestic species, which presented several imp...
Research on humans is limited, therefore human animal chimeras have been used to study human systems...
The development of human pluripotent stem cells has opened up the possibility to analyse the functio...
All organisms depend on stem cells for their survival. As a result, stem cells may be a prerequisite...
Embryonic pluripotency can be recapitulated in vitro by a spectrum of pluripotent stem cell states s...
The generation of radiation chimeras allows researchers to substitute the hematopoietic system of a ...
The remarkable similarity between non-human primates (NHPs) and humans establishes them as essential...
Stem cells research is becoming a very interesting field for investigation and experimental studies....
In recent years, there has been an explosion of interest in stem cells, not just within the scientif...
Stem cells (SC) research is an important part of biotechnology that could lead to the development of...