Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands

Neumann, Eberhard
Nolte, Hans-Jürgen

January 1981

Neumann E, Nolte H-J. Polyelectrolyte field effects. Bioelectrochemistry and Bioenergetics. 1981;8(1...

Characterization of the Active Site of Acetylcholinesterases by Application of Sterically Modified Acetylcholine Homologues

W. H. Hopff
G. Riggio
A. Hofmann
P. G. Waser

January 1975

Our aim was to find steric limitations for the model of the active site of acetylcholinesterase and ...

Electrostatic Steering at Acetylcholine Binding Sites

Theodore G. Wensel
Y James M. Briggs
Steen E. Pedersen

January 2015

ABSTRACT The electrostatic environments near the acetylcholine binding sites on the nicotinic acetyl...

Interaction of Ligand Binding Sites of Acetylcholinesterase

Gregory Mooser
David S. Sigman

January 1975

Ligand binding properties of acetylcholinesterase from Electrophorus electricus have been investigat...

Interaction of ligands with acetylcholinesterase. Use of temperature-jump relaxation kinetics in the binding of specific fluorescent ligands

Rosenberry, Terrone L.
Neumann, Eberhard

January 1977

Rosenberry TL, Neumann E. Interaction of ligands with acetylcholinesterase. Use of temperature-jump ...

Electrostatic Steering at Acetylcholine Binding Sites

Meltzer, Robert H.
Thompson, Errol
Soman, Kizhake V.
Song, Xing-Zhi
Ebalunode, Jerry O.
Wensel, Theodore G.
Briggs, James M.
Pedersen, Steen E.

August 2006

AbstractThe electrostatic environments near the acetylcholine binding sites on the nicotinic acetylc...

Acetylcholinesterase: diffusional encounter rate constants for dumbbell models of ligand

Antosiewicz, J.
Gilson, M.K.
Lee, I.H.
McCammon, J.A.

January 1995

For some enzymes, virtually every substrate molecule that encounters the entrance to the active site...

Molecular Structure and Catalytic Activity of Membrane-Bound Acetylcholinesterase from Electric Organ Tissue of the Electric Eel

Isriael Silman
Yadin Dudai

January 1975

The catalytic activity of membrane-bound acetylcholinesterase in electric organ tissue was shown to ...

A Modular Treatment of Molecular Traffic Through the Active Site of Cholinesterase

Botti, Simone A.
Felder, Clifford E.
Lifson, Shneior
Sussman, Joel L.
Silman, Israel

November 1999

AbstractWe present a model for the molecular traffic of ligands, substrates, and products through th...

Spectroscopic Studies of Ligand Interactions with Acetycholinesterase

Palmer Taylor
Jamson Lwebuga-Mukasa
Harvey Berman
Shelley Lappi

January 1975

A series of ligands with suitable spectroscopic properties have been employed for investigating the ...

Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity

ESTEVEZ, JORGE
Marina, Terol
SOGORB, MIGUEL A
Vilanova, Eugenio

December 2021

Phenyl valerate (PV) is a neutral substrate for measuring the PVase activity of neuropathy target es...

Influence of the Water Structure on the Acetylcholinesterase Efficiency

Ramos, Angela S.F.
Techert, Simone

September 2005

AbstractWe have studied the catalytic efficiency of acetylcholinesterase (AChE) in various solutions...

Molecular modelling studies of acetylcholinesterase

Linaras, Charilaos E.

April 1998

The controversial role of electrostatic interactions in the process of steering of acetylcholine int...

Molecular recognition by acetylcholinesterase at the peripheral anionic site: Structure-activity relationships for inhibitions by aryl carbamates

Lin, G.L.
Lai, C.Y.
Liao, W.C.

June 2014

Substituted phenyl-N-butyl carbamates (1-9) are potent irreversible inhibitors of Electrophorus elec...

SUMMARY

George Tomlinson
Bulent Mutus
Ian Mclennan
B. Mutus

January 1979

activity by peripheral site ligands Mol. Pharmacol. 18: 33-39 (1980). The steady-state hydrolysis of...

Polyelectrolyte field effects

Neumann, Eberhard
Nolte, Hans-Jürgen

January 1981

Neumann E, Nolte H-J. Polyelectrolyte field effects. Bioelectrochemistry and Bioenergetics. 1981;8(1...

Characterization of the Active Site of Acetylcholinesterases by Application of Sterically Modified Acetylcholine Homologues

W. H. Hopff
G. Riggio
A. Hofmann
P. G. Waser

January 1975

Our aim was to find steric limitations for the model of the active site of acetylcholinesterase and ...

Electrostatic Steering at Acetylcholine Binding Sites

Theodore G. Wensel
Y James M. Briggs
Steen E. Pedersen

January 2015

ABSTRACT The electrostatic environments near the acetylcholine binding sites on the nicotinic acetyl...

Interaction of Ligand Binding Sites of Acetylcholinesterase

Gregory Mooser
David S. Sigman

January 1975

Ligand binding properties of acetylcholinesterase from Electrophorus electricus have been investigat...

Interaction of ligands with acetylcholinesterase. Use of temperature-jump relaxation kinetics in the binding of specific fluorescent ligands

Rosenberry, Terrone L.
Neumann, Eberhard

January 1977

Rosenberry TL, Neumann E. Interaction of ligands with acetylcholinesterase. Use of temperature-jump ...

Electrostatic Steering at Acetylcholine Binding Sites

Meltzer, Robert H.
Thompson, Errol
Soman, Kizhake V.
Song, Xing-Zhi
Ebalunode, Jerry O.
Wensel, Theodore G.
Briggs, James M.
Pedersen, Steen E.

August 2006

AbstractThe electrostatic environments near the acetylcholine binding sites on the nicotinic acetylc...

Acetylcholinesterase: diffusional encounter rate constants for dumbbell models of ligand

Antosiewicz, J.
Gilson, M.K.
Lee, I.H.
McCammon, J.A.

January 1995

For some enzymes, virtually every substrate molecule that encounters the entrance to the active site...

Molecular Structure and Catalytic Activity of Membrane-Bound Acetylcholinesterase from Electric Organ Tissue of the Electric Eel

Isriael Silman
Yadin Dudai

January 1975

The catalytic activity of membrane-bound acetylcholinesterase in electric organ tissue was shown to ...

A Modular Treatment of Molecular Traffic Through the Active Site of Cholinesterase

Botti, Simone A.
Felder, Clifford E.
Lifson, Shneior
Sussman, Joel L.
Silman, Israel

November 1999

AbstractWe present a model for the molecular traffic of ligands, substrates, and products through th...

Spectroscopic Studies of Ligand Interactions with Acetycholinesterase

Palmer Taylor
Jamson Lwebuga-Mukasa
Harvey Berman
Shelley Lappi

January 1975

A series of ligands with suitable spectroscopic properties have been employed for investigating the ...

Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity

ESTEVEZ, JORGE
Marina, Terol
SOGORB, MIGUEL A
Vilanova, Eugenio

December 2021

Phenyl valerate (PV) is a neutral substrate for measuring the PVase activity of neuropathy target es...

Influence of the Water Structure on the Acetylcholinesterase Efficiency

Ramos, Angela S.F.
Techert, Simone

September 2005

AbstractWe have studied the catalytic efficiency of acetylcholinesterase (AChE) in various solutions...

Molecular modelling studies of acetylcholinesterase

Linaras, Charilaos E.

April 1998

The controversial role of electrostatic interactions in the process of steering of acetylcholine int...

Molecular recognition by acetylcholinesterase at the peripheral anionic site: Structure-activity relationships for inhibitions by aryl carbamates

Lin, G.L.
Lai, C.Y.
Liao, W.C.

June 2014

Substituted phenyl-N-butyl carbamates (1-9) are potent irreversible inhibitors of Electrophorus elec...

SUMMARY

George Tomlinson
Bulent Mutus
Ian Mclennan
B. Mutus

January 1979

activity by peripheral site ligands Mol. Pharmacol. 18: 33-39 (1980). The steady-state hydrolysis of...

Polyelectrolyte field effects

Neumann, Eberhard
Nolte, Hans-Jürgen

January 1981

Neumann E, Nolte H-J. Polyelectrolyte field effects. Bioelectrochemistry and Bioenergetics. 1981;8(1...

Characterization of the Active Site of Acetylcholinesterases by Application of Sterically Modified Acetylcholine Homologues

W. H. Hopff
G. Riggio
A. Hofmann
P. G. Waser

January 1975

Our aim was to find steric limitations for the model of the active site of acetylcholinesterase and ...

Electrostatic Steering at Acetylcholine Binding Sites

Theodore G. Wensel
Y James M. Briggs
Steen E. Pedersen

January 2015

ABSTRACT The electrostatic environments near the acetylcholine binding sites on the nicotinic acetyl...

Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands

Abstract

Extracted data

Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands

Abstract

Extracted data

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