Keilwagen J, Baumbach J, Kohl TA, Grosse I. MotifAdjuster: a tool for computational reassessment of transcription factor binding site annotations. Genome Biology. 2009;10(5):R46.Valuable binding-site annotation data are stored in databases. However, several types of errors can, and do, occur in the process of manually incorporating annotation data from the scientific literature into these databases. Here, we introduce MotifAdjuster http://dig.ipk-gatersleben.de/MotifAdjuster.html webcite, a tool that helps to detect these errors, and we demonstrate its efficacy on public data sets
The human genome contains roughly 1,600 transcription factors (TFs) (1), DNA-binding proteins recogn...
Transcription factor binding sites (TFBSs) are DNA sequences of 6 to 15 base pairs and interaction w...
[eng] Gene expression is a complex and highly regulated process. Most of the regulation is controll...
Keilwagen J, Baumbach J, Kohl TA, Grosse I. MotifAdjuster: a tool for computational reassessment of ...
Transcription factor (TF) binding site prediction remains a challenge in gene regulatory research du...
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mos...
Background An important step in annotation of sequenced genomes is the identification of transcri...
[[abstract]]Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of ...
Background: A precise experimental identification of transcription factor binding motifs (TFBMs), ac...
Understanding the mechanisms that regulate gene expression is a major challenge in biology. One of t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
IMAGE is an application tool, based on the vector quantization method, aiding the discovery of nucle...
Background: Transcriptional regulation is an important part of regulatory control in eukaryotes. Eve...
Background: Computational tools for the investigation of transcriptional regulation, in particular o...
International audienceEukaryotic genomes contain a variety of structured patterns: repetitive elemen...
The human genome contains roughly 1,600 transcription factors (TFs) (1), DNA-binding proteins recogn...
Transcription factor binding sites (TFBSs) are DNA sequences of 6 to 15 base pairs and interaction w...
[eng] Gene expression is a complex and highly regulated process. Most of the regulation is controll...
Keilwagen J, Baumbach J, Kohl TA, Grosse I. MotifAdjuster: a tool for computational reassessment of ...
Transcription factor (TF) binding site prediction remains a challenge in gene regulatory research du...
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mos...
Background An important step in annotation of sequenced genomes is the identification of transcri...
[[abstract]]Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of ...
Background: A precise experimental identification of transcription factor binding motifs (TFBMs), ac...
Understanding the mechanisms that regulate gene expression is a major challenge in biology. One of t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
IMAGE is an application tool, based on the vector quantization method, aiding the discovery of nucle...
Background: Transcriptional regulation is an important part of regulatory control in eukaryotes. Eve...
Background: Computational tools for the investigation of transcriptional regulation, in particular o...
International audienceEukaryotic genomes contain a variety of structured patterns: repetitive elemen...
The human genome contains roughly 1,600 transcription factors (TFs) (1), DNA-binding proteins recogn...
Transcription factor binding sites (TFBSs) are DNA sequences of 6 to 15 base pairs and interaction w...
[eng] Gene expression is a complex and highly regulated process. Most of the regulation is controll...