Purpose: Although standard treatment with transurethral resection and intravesical therapy (IVT) is known to be effective to address the clinical behavior of non-muscle-invasive bladder cancer (NMIBC), many patients fail to respond to the treatment and frequently experience disease recurrence. Here, we aim to identify a prognostic molecular signature that predicts the NMIBC heterogeneity and response to IVT. Experimental Design: We analyzed the genomic profiles of 102 patients with NMIBC to identify a signature associated with disease recurrence. The validity of the signature was verified in three independent patient cohorts (n = 658). Various statistical methods, including a leave-one-out cross-validation and multivariate Cox regression an...
textabstractBackground: Multiple clinical risk factors and genetic profiles have been demonstrated t...
Contains fulltext : 165718.pdf (publisher's version ) (Closed access)OBJECTIVE: Th...
BACKGROUND: Multiple clinical risk factors and genetic profiles have been demonstrated to predict pr...
Bladder cancer (BC) is one of the most expensive lifetime cancers to treat because of the high recur...
UnrestrictedUrothelial carcinoma of the urinary bladder is the seventh most common type of cancer wo...
To evaluate the utility of different risk assessments in non-muscle-invasive bladder cancer (NMIBC) ...
PURPOSE: In approximately 20% of patients with superficial bladder tumors, the tumors progress to in...
Abstract Background Bladder cancer (BC) is one of the most common malignancies and has a relatively ...
In bladder cancer, clinical grade and stage fail to capture outcome. We developed a clinically appli...
The proto-oncogene forkhead box M1 (FOXM1) is associated with poor survival in many cancers. The imp...
Bladder cancer is a biologically heterogeneous disease with variable clinical presentations, outcome...
Purpose. The complex etiological variables and high heterogeneity of bladder cancer (BC) make progno...
© Translational Andrology and Urology. Bladder cancer (BC) is a common disease in both sexes and maj...
It remains unclear how to implement the recently revealed basal and luminal subtypes of muscle-invas...
Background: Non-muscle-invasive bladder cancer (NMIBC) is characterized by frequent recurrences and ...
textabstractBackground: Multiple clinical risk factors and genetic profiles have been demonstrated t...
Contains fulltext : 165718.pdf (publisher's version ) (Closed access)OBJECTIVE: Th...
BACKGROUND: Multiple clinical risk factors and genetic profiles have been demonstrated to predict pr...
Bladder cancer (BC) is one of the most expensive lifetime cancers to treat because of the high recur...
UnrestrictedUrothelial carcinoma of the urinary bladder is the seventh most common type of cancer wo...
To evaluate the utility of different risk assessments in non-muscle-invasive bladder cancer (NMIBC) ...
PURPOSE: In approximately 20% of patients with superficial bladder tumors, the tumors progress to in...
Abstract Background Bladder cancer (BC) is one of the most common malignancies and has a relatively ...
In bladder cancer, clinical grade and stage fail to capture outcome. We developed a clinically appli...
The proto-oncogene forkhead box M1 (FOXM1) is associated with poor survival in many cancers. The imp...
Bladder cancer is a biologically heterogeneous disease with variable clinical presentations, outcome...
Purpose. The complex etiological variables and high heterogeneity of bladder cancer (BC) make progno...
© Translational Andrology and Urology. Bladder cancer (BC) is a common disease in both sexes and maj...
It remains unclear how to implement the recently revealed basal and luminal subtypes of muscle-invas...
Background: Non-muscle-invasive bladder cancer (NMIBC) is characterized by frequent recurrences and ...
textabstractBackground: Multiple clinical risk factors and genetic profiles have been demonstrated t...
Contains fulltext : 165718.pdf (publisher's version ) (Closed access)OBJECTIVE: Th...
BACKGROUND: Multiple clinical risk factors and genetic profiles have been demonstrated to predict pr...