A biochip based on magnetoresistive sensors

Schotter J, Kamp P-B, Becker A, et al. A biochip based on magnetoresistive sensors. In: IEEE Transactions on Magnetics. IEEE TRANSACTIONS ON MAGNETICS. Vol 38. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC; 2002: 3365-3367.The signal response of Bangs Laboratories magnetic markers with a mean diameter of 0.86 mum on a spiral-shaped giant magnetoresistance sensor with a diameter of 70 mum is investigated. The data show a linear dependence of the sensor signal on the surface coverage of the magnetic markers. The detection limit is reached at a coverage of about 5%, which corresponds to about 200 markers distributed across the surface of the sensor. The corresponding molecular binding of the analyte DNA and the magnetic markers show good selectivity and sensitivity