Cassane diterpenoids from Lonchocarpus laxiflorus

Igoli JO, Onyiriuka SO, Letzel M, Nwaji MN, Gray AI. Cassane diterpenoids from Lonchocarpus laxiflorus. NATURAL PRODUCT COMMUNICATIONS. 2008;3(1):5-10.Phytochemical investigation of the stem bark of Lonchocarpus laxiflorus yielded three new cassane diterpenoids, lonchocassane A [cassa-13 (14), 15-dien-18, 20-dioic acid], lonchocassane B [cassa-13 (14), 15-dien-20-oxo-18-oic acid] and lonchocassane C [cassa-13 (14), 15-dien-20-carboxyl-18-methylcarboxylate]. The known compounds. betulinic acid, betulinic acid acetate, betulin, lupeol, lupenone, trilinoleate, hexacosanyl and triacontanyl caffeates, 4-hydroxy-4-methylpentan-2-one, beta-sitosterol, beta-sitosterol acetate and stigmasterol were also isolated. The structures and identities of the compounds were established by spectroscopic methods