Gröger H, Hummel W, Metzner R. Asymmetric Biocatalytic Reduction of Ketones. In: Carreira EM, Yamamoto H, eds. Synthetic Methods VI – Enzymatic and Semi-Enzymatic. Comprehensive Chirality. Vol 7. Oxford: Elsevier; 2012: 181-215.The use of enzymes as catalysts in enantioselective ketone reduction has gained broad synthetic interest in organic chemistry since this biocatalytic methodology was found to be a versatile, robust, efficient, and industrially feasible synthetic approach toward enantiomerically pure alcohols. In such processes, which are based on the use of isolated enzymes, immobilized enzymes, and recombinant whole-cell catalysts, respectively, different types of cofactor regenerations based in particular on substrate- and enzyme-...
Chiral β-nitroalcohols are important building blocks in organic chemistry. The synthetic approa...
Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formatio...
Biotransformation reactions of many organic compounds under the influence of enzymes take place with...
Gröger H, Borchert S, Kraußer M, Hummel W. Enzyme-Catalyzed Asymmetric Reduction of Ketones. In: Fli...
Alcohol dehydrogenases or carbonyl reductases have been extensively developed for the asymmetric red...
Enzymes are able to perform reactions under mild conditions, e.g., pH and temperature, with remarkab...
Gröger H, Hummel W, Buchholz S, et al. Practical asymmetric enzymatic reduction through discovery of...
Catalytic asymmetric reduction of prochiral ketones with the formation of enantio-pure secondary alc...
In der vorliegenden Arbeit wird die Entwicklung eines Verfahrens zur biokatalytischen Reduktion proc...
Gluconobacter oxydans (ATCC 621) were permeabilized with toluene and then lyophilized. This crude en...
Bioreduction has emerged over the years as an alternative method to organic synthesis for the genera...
Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formatio...
The reduction of methyl acetoacetate was carried out in continuously operated biotransformation proc...
Whole-cell biocatalysts offer a highly enantioselective, minimally polluting route to optically acti...
Effective procedures for the synthesis of optically pure alcohols are highly valuable. A commonly em...
Chiral β-nitroalcohols are important building blocks in organic chemistry. The synthetic approa...
Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formatio...
Biotransformation reactions of many organic compounds under the influence of enzymes take place with...
Gröger H, Borchert S, Kraußer M, Hummel W. Enzyme-Catalyzed Asymmetric Reduction of Ketones. In: Fli...
Alcohol dehydrogenases or carbonyl reductases have been extensively developed for the asymmetric red...
Enzymes are able to perform reactions under mild conditions, e.g., pH and temperature, with remarkab...
Gröger H, Hummel W, Buchholz S, et al. Practical asymmetric enzymatic reduction through discovery of...
Catalytic asymmetric reduction of prochiral ketones with the formation of enantio-pure secondary alc...
In der vorliegenden Arbeit wird die Entwicklung eines Verfahrens zur biokatalytischen Reduktion proc...
Gluconobacter oxydans (ATCC 621) were permeabilized with toluene and then lyophilized. This crude en...
Bioreduction has emerged over the years as an alternative method to organic synthesis for the genera...
Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formatio...
The reduction of methyl acetoacetate was carried out in continuously operated biotransformation proc...
Whole-cell biocatalysts offer a highly enantioselective, minimally polluting route to optically acti...
Effective procedures for the synthesis of optically pure alcohols are highly valuable. A commonly em...
Chiral β-nitroalcohols are important building blocks in organic chemistry. The synthetic approa...
Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formatio...
Biotransformation reactions of many organic compounds under the influence of enzymes take place with...