Adenosine receptor plays very important role in regulation of immune response. Its signalling may lead to initiation of metabolic switch, which suppresses energy consumption by peripheral tissues (selfish behaviour of immunes system). In this thesis I attempt to test the potential role of adenosine signalling in self-activation of immune cells which could alternatively explain its role in systemic energetic switch in model organism Drosophila melanogaster
<div><p>Phagocytosis by hemocytes, <i>Drosophila</i> macrophages, is essential for resistance to <i>...
Adenosine deaminase (ADA) is an enzyme present in all organisms that catalyzes the irreversible deam...
In previous studies the extracellular adenosine has been proved as an important signaling molecule c...
<div><p>Immune defense is energetically costly, and thus an effective response requires metabolic ad...
The aim of this thesis was to investigate the tissue specific role of adenosine receptor in larvae o...
This thesis describes several aspects of the role for extracellular adenosine in Drosophila. Reverse...
This thesis characterizes adenosine signalization in Drosophila and describes response to adenosine ...
Immune defense is energetically costly, and thus an effective response requires metabolic adaptation...
Adenosine is a ubiquitous metabolite with multiple physiological functions in organisms. In this the...
Phagocytosis by hemocytes, Drosophila macrophages, is essential for resistance to Streptococcus pneu...
The molecular components of the purinergic system (i.e., receptors, metabolizing enzymes and membran...
Life history theory predicts that trait evolution should be constrained by competing physiological d...
Extra-cellular adenosine is an important regulator of inflammatory responses. It is generated from r...
The expression of adenosine deaminase related growth factor A (ADGF-A) during immune response was st...
Regulation of adenosine deaminase-related growth factor A (ADGF-A) expression was studied by prepari...
<div><p>Phagocytosis by hemocytes, <i>Drosophila</i> macrophages, is essential for resistance to <i>...
Adenosine deaminase (ADA) is an enzyme present in all organisms that catalyzes the irreversible deam...
In previous studies the extracellular adenosine has been proved as an important signaling molecule c...
<div><p>Immune defense is energetically costly, and thus an effective response requires metabolic ad...
The aim of this thesis was to investigate the tissue specific role of adenosine receptor in larvae o...
This thesis describes several aspects of the role for extracellular adenosine in Drosophila. Reverse...
This thesis characterizes adenosine signalization in Drosophila and describes response to adenosine ...
Immune defense is energetically costly, and thus an effective response requires metabolic adaptation...
Adenosine is a ubiquitous metabolite with multiple physiological functions in organisms. In this the...
Phagocytosis by hemocytes, Drosophila macrophages, is essential for resistance to Streptococcus pneu...
The molecular components of the purinergic system (i.e., receptors, metabolizing enzymes and membran...
Life history theory predicts that trait evolution should be constrained by competing physiological d...
Extra-cellular adenosine is an important regulator of inflammatory responses. It is generated from r...
The expression of adenosine deaminase related growth factor A (ADGF-A) during immune response was st...
Regulation of adenosine deaminase-related growth factor A (ADGF-A) expression was studied by prepari...
<div><p>Phagocytosis by hemocytes, <i>Drosophila</i> macrophages, is essential for resistance to <i>...
Adenosine deaminase (ADA) is an enzyme present in all organisms that catalyzes the irreversible deam...
In previous studies the extracellular adenosine has been proved as an important signaling molecule c...