Synthesis and structural studies of 5, 11, 17, 23-tetrahydroxyresorc[4]arenes

Gerkensmeier T, Agena C, Iwanek W, et al. Synthesis and structural studies of 5, 11, 17, 23-tetrahydroxyresorc[4]arenes. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES. 2001;56(10):1063-1073.Hydroxyresorc[4]arenes are bowl-shaped calixarene compounds. Herein we report the synthesis and the results of X-ray diffraction examinations of six hydroxyresorc[4]arenes, one of them could be crystallized in two conformations. All compounds co-crystallize with different solvent molecules, linked together by hydrogen bonds. It is known that hydroxyresorc[4]arenes are capable of forming large aggregates, a number of different compounds have been prepared, some of them could be crystallized and investigated by single crystal methods. Most of the compounds tend to form polarity-induced double layers