The product of the human C21orf57 (huYBEY) gene is predicted to be a homologue of the highly conserved YbeY proteins found in nearly all bacteria. We show that, like its bacterial and chloroplast counterparts, the HuYbeY protein is an RNase and that it retains sufficient function in common with bacterial YbeY proteins to partially suppress numerous aspects of the complex phenotype of an Escherichia coli ΔybeY mutant. Expression of HuYbeY in Saccharomyces cerevisiae, which lacks a YbeY homologue, results in a severe growth phenotype. This observation suggests that the function of HuYbeY in human cells is likely regulated through specific interactions with partner proteins similarly to the way YbeY is regulated in bacteria.National Institutes...
The SMc01113/YbeY protein, belonging to the UPF0054 family, is highly conserved in nearly every bact...
Many genes in bacterial genomes are of unknown function, often referred to as y-genes. Recently, the...
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrat...
YbeY, a highly conserved protein, is an RNase in E. coli and plays key roles in both processing of t...
The UPF0054 protein family is highly conserved with homologs present in nearly every sequenced bacte...
The UPF0054 protein family is highly conserved with homologues present in nearly every sequenced bac...
ABSTRACT YbeY is part of a core set of RNases in Escherichia coli and other bacteria. This highly co...
YbeY, a highly conserved protein, is an RNase in E. coli and plays key roles in both processing of t...
YbeY is part of a core set of RNases in Escherichia coli and other bacteria. This highly conserved e...
YbeY is a highly conserved RNase in bacteria and plays essential roles in the maturation of 16S rRNA...
The endoribonuclease YbeY is one of the most well conserved proteins across the kingdoms of life. In...
Posttranscriptional regulation plays an essential role in the quick adaptation of pathogenic bacteri...
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrat...
A new group of translation-associated heat shock genes has been recently identified. One of these no...
ABSTRACT Posttranscriptional regulation plays an essential role in the quick adaptation of pathogeni...
The SMc01113/YbeY protein, belonging to the UPF0054 family, is highly conserved in nearly every bact...
Many genes in bacterial genomes are of unknown function, often referred to as y-genes. Recently, the...
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrat...
YbeY, a highly conserved protein, is an RNase in E. coli and plays key roles in both processing of t...
The UPF0054 protein family is highly conserved with homologs present in nearly every sequenced bacte...
The UPF0054 protein family is highly conserved with homologues present in nearly every sequenced bac...
ABSTRACT YbeY is part of a core set of RNases in Escherichia coli and other bacteria. This highly co...
YbeY, a highly conserved protein, is an RNase in E. coli and plays key roles in both processing of t...
YbeY is part of a core set of RNases in Escherichia coli and other bacteria. This highly conserved e...
YbeY is a highly conserved RNase in bacteria and plays essential roles in the maturation of 16S rRNA...
The endoribonuclease YbeY is one of the most well conserved proteins across the kingdoms of life. In...
Posttranscriptional regulation plays an essential role in the quick adaptation of pathogenic bacteri...
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrat...
A new group of translation-associated heat shock genes has been recently identified. One of these no...
ABSTRACT Posttranscriptional regulation plays an essential role in the quick adaptation of pathogeni...
The SMc01113/YbeY protein, belonging to the UPF0054 family, is highly conserved in nearly every bact...
Many genes in bacterial genomes are of unknown function, often referred to as y-genes. Recently, the...
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrat...